Hey, first of all, sorry, I'm sure you get these threads all too often. I've scanned the forums yet found no answers to my problem. I'm hoping you guys could help me out.
I have lots of mods. It goes without saying that incompatibility and unstability is the problem here. I get random crashes, often, sometimes I can run the game for 30 mins fault free, sometimes I have to reload every 2 mins. Most of the crashes, I've noticed, occur when upon opening a door to a new cell, the game tries to autosave. So, mostly just crashes to desktop, but I've also got the crashes where the game freezes. The curious thing I haven't got a crash that would break the game (I've always got past the points when loading again), until now!
You see, whenever I come to the "Super Duper Mart", close to Megaton, and talk to the Ghoul wastelander about sharing the water (I have high speech skill ), when the game should add the water to my inventory, I get nothing, instead the game crashes to desktop after realizing I didn't get any item. (the wanderer just says "get out of here you already got your water")
Here is my load order, maybe some of you experienced FO3 mod users know what could be causing the crash? I'm leaning towards the Wanderers Edition, as far as I'm aware, this would be the mod responsible for the water that didnt exist.

Thank you very much!

fallout3.esm
Fallout3.esm
Anchorage.esm
ThePitt.esm
BrokenSteel.esm
PointLookout.esm
Zeta.esm
iHUD.esm
CRAFT.esm
CALIBR.esm
FO3 Wanderers Edition - Main File.esm
EVE.esm
Mart's Mutant Mod.esm
StreetLights.esm
DCInteriors_ComboEdition.esm
DCInteriors_SideQuests.esm
DYNAVISION - Dynamic Lens Effect.esp
Owned!.esp
FO3 Wanderers Edition - Main File.esp
FO3 Wanderers Edition - DLC Anchorage.esp
FO3 Wanderers Edition - DLC Broken Steel.esp
FO3 Wanderers Edition - DLC Mothership Zeta.esp
FO3 Wanderers Edition - DLC Point Lookout.esp
FO3 Wanderers Edition - DLC The Pitt.esp
FO3 Wanderers Edition - Followers Enhanced (BrokenSteel).esp
FO3 Wanderers Edition - Alternate Travel.esp
WeaponModKits.esp
WeaponModKits - FWE Master Release.esp
WeaponModKits - OperationAnchorage.esp
WeaponModKits - ThePitt.esp
WeaponModKits - BrokenSteel.esp
WeaponModKits - PointLookout.esp
WeaponModKits - Zeta.esp
EVE.esp
EVE Operation Anchorage.esp
EVE - FWE Master Release.esp
EVE - FWE Master Release (Follower Enhanced).esp
EVE - FWE Master Release (pulse fix).esp
EVE - FWE with WeaponModKits.esp
EVE Anchorage - FWE DLC Anchorage.esp
Mart's Mutant Mod.esp
Mart's Mutant Mod - DLC Anchorage.esp
Mart's Mutant Mod - DLC Point Lookout.esp
Mart's Mutant Mod - DLC The Pitt.esp
Mart's Mutant Mod - DLC Broken Steel.esp
Mart's Mutant Mod - DLC Zeta.esp
Mart's Mutant Mod - Master Menu Module.esp
Mart's Mutant Mod - Natural Selection.esp
Mart's Mutant Mod - Tougher Traders.esp
Mart's Mutant Mod - Zones Respawn.esp
Mart's Mutant Mod - FWE Master Release.esp
Mart's Mutant Mod - FWE Master Release + DLCs.esp
F3ProjectRealityMkI.esp
MTC Wasteland Travellers (Optional)- Crowded Cities.esp
MTC Wasteland Travellers.esp
MTC Wasteland Travellers (Optional)- Crowded Cities less NPCs.esp
DCInteriors_DLC_Collectables.esp
mutantradio.esp

Maybe not related,but why do you have 2 Fallout 3 ESM Files?

Hey, I just installed Fallout 3 GOTY and it starts up, but then when I press "New Game" the whole game crashes shortly after. I never even get into the actual game. PLEASE HELP! It says this error message:
Problem signature:
Problem Event Name: APPCRASH

Application Name: Fallout3.exe

Application Version: 1.7.0.3

Application Timestamp: 4a40f18b

Fault Module Name: Fallout3.exe

Fault Module Version: 1.7.0.3

Fault Module Timestamp: 4a40f18b

Exception Code: c0000005

Exception Offset: 006ddf7b

OS Version: 6.1.7601.2.1.0.768.3

Locale ID: 1033

Additional Information 1: 0a9e

Additional Information 2: 0a9e372d3b4ad19135b953a78882e789

Additional Information 3: 0a9e

Additional Information 4: 0a9e372d3b4ad19135b953a78882e789