So I got Oblivion: GOTY Deluxe edition from the Steam Summer Sale a while back and for about a week the game worked, had accumulated a decent amount of mods I wanted and still had no trouble running the game. Then I went out of town for a few days and when I got back Oblivion just stopped working. It won't load and it will just give an "Oblivion has stopped working" pop up. I tried disabling all my mods and still it gives me the error. Whats going on?

Nowhere near enough data to work with. Run some searches for the same question and see what you need to add, if the searches don't have the answers.