Hmm, DX11 and HRTP made some interesting things to some players, while enabled. Make sure you have the latest drivers installed for your setup. On the other hand, does your video card support DX11? If not, you won't be able to turn it on, the button will still remain inactive. As for the HRTP, I don't know why it won't give you an option to turn it on. One thing that always works for me is reinstalling the whole game.
But if you have some time, wait for a person who's more experienced or have a sollution to your problem, personally, I did not have any during using them in-game.