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1) Build:
Strength: 7
Perception: 4
Endurance: 7
Charisma: 5
Intelligence: 7
Agility: 5
Luck: 5
(More points can be added later via Intense Training, but this is a good start)
Tagged Skills:
Repair
Medicine
Lockpicking
When you Level up, spend points in the Tagged Skills and Barter. You'll need this for later. Get the Intense Training Perk and spend the Point in Agility or Luck.
2) After completing the quests in Goodsprings, cross I-15 and continue along the road that leads to Hidden Valley. Complete the Brotherhood of Steel questline to get the Power Armor Training. If you level up, spend the Points in Energy Weapons and Barter. Sell off everything you don't need and Buy the Non-faction T-51b Armor. Use the T-45d armor to Repair your T-51b. Accuire a Gauss Rifle if you can, if you can't don't worry, you'll get one later on.
3) Procede on with the Main quest until you reach the REPCONN Headquarters, acquire the Q-35 Matter Modulator and whatever loot you can find. Make sure you are spending your points in essintial skills (Tagged Skills, EW, Guns, Speech, and Barter) and Perks that Give you more Damage to your weapons and allow ammo recovery and carry more weight.
4) At Freeside, Sell off the things you have been gathering to sell to earn money to purchase resorces and other crap.
5) Procede to the Brotherhood Safehouse and Gather the Gauss Rifle and Tesla Coil. From here, go East to The Devil's Throat and Acquire The CZ57 Avenger Minigun.
If you have been spending your perks wisely, Then You have Just become the most powerful Courier in the Mojave at the Early stages of the Game. I hope it helps you out.