I am having issues with playing the level Gods and Monsters.
I had a bunch of random crashes in that level or while loading, but now I have found a crash that can be reproduced: The game crashes every single time I reach a certain point IF I trigger the creation of a optional mission by opening a cell container and tag the location of the optional mission with the visior. Not creating or tagging the mission so far has always worked.

These are my objectives, including the optional mission:

http://i.imgur.com/QygbBan.jpg

This is where I am coming from:

http://i.imgur.com/ocGLR2x.jpg

This is where I want to go:

http://i.imgur.com/uYE57yU.jpg

This is how it always ends when I go a bit further:

http://i.imgur.com/0NgCZPj.jpg

Is this a known issue?

Playing on:

Radon 7850/2G
Core i5 3550
16GB Ram
1920x1080 maxed graphic, no AA

Here is the savegame:
http://en.file-upload.net/download-7311545/SaveGames.zip.html

Go forward, hack the red container, tag the optional mission and follow resulted in a crash like 5 times in a row. Not opening the container or at least not tagging the optional mission seems to work.