Werewolves have appeared in 3 TES entries of 5 excluding Battlespire and Redguard.
I already consider them a moderate staple as they're tied to one if the Daedra Lord.
Yes, werewolves were in two of the previous numbered entries, Daggerfall and Morrowind's Bloodmoon expansion, so they've been kind of a staple for a long time now. Vampires have been in the series since day one with Arena, but Daggerfall was the first entry to allow the player to become one.