FIX:
for to fix crashes (usual crashes) just look for event monitor if you get a WHEA Error before application crash and if yes, increase your CPU Core, VTT and DRAM Voltage a bit then before playing game max your gpu voltage if you are using GTX 600 its 1.175 if you mod it its 1.21.. if you are using GTX 400-500 and OC ing or not, up your voltage a bit.
Thats it, and look for the event monitor for WHEA errors too frequently.
note: the reason behind this method is that sometimes drivers/games can lead our systems to crash even if its stable already so its fine to up the voltages a bit.
edit: also stop any useless background processes and maybe disable any OSD Server.
for smoothness in any settings:
nvidia last drivers + panel settings to default and use max performance and also optionally clamp high quality.
in-game vsync off(broken anyway)
d3doverrider vsync + triple buffer
fps limiter to refresh rate like cap at 60 FPS. nothing below just refresh rate. this will smooth out the lag caused by vsync and triple buffer but if you use lower than refresh rate you notice hitching.
use timerresolution maximum
.. same thing can go to other games too but if other games vsync is not broken then no need to use d3doverrider.