I also experienced this problem, and I know I was using EL&FX, but I can't remember if I was also using an ENB. It was most noticeable in Dragonsreach when looking at the big fire pit in the middle of the hall towards the front doors. Looking to one side and then the other would cause the light from the pit to flash on/off.
Come to think of it, I recently experienced the same thing in High Hrothgar with a sconce by the back doors to the courtyard. This time not using EL&FX but using an ENB (can't remember which preset, using ENB 1.19).