I know it will have multiplayer unless plans were changed.
http://123kinect.com/ryse-update-multiplayer-confirmed/36766/
I am afraid there won't be real skill in this game and it will all come down to luck. Hopefully it is responsive enough, the problem is how would you actually move around the game world in multiplayer? From what little that has been shown of the game the single player looks like your character moves around automatically.