So I must have really screwed something here. After installing New Vegas Redesigned and some other things I got crashes on startup. No biggie, lets re activate uHud and run BOSS, see if it is just something trivial. Still a crash. So at this point I'm launching FNV Edit and whaddaya know, I get an error there, too.
Editing is disable because there was a fatal error while loading the mods:
[00:03] Background Loader: Fatal:
The system cannot find the file specified>
I don't know how to handle this and would really like some advice. I will give my load order if you need it.