I have, and my game runs as smooth as milk...in fact, it actually cleared up some of the problems, such as the breezehome lockout glitch.
Skyrim crashes after 10 - 15 minutes of gameplay, I have to manually reboot. i had downloaded it from several people same problem. I like Skyrim so much I bought the Legendary Edition and it is on Steam. I have several games on Steam. To my surprize same problem. Any solutions?
My Rig: i7 360 3.2GHz, 7970 radeon, 12 GB Cosair Vengence 1600 MHz, 950 Watts Cosair 950TX, X-Fi Xtreme Gamer 24BIT, ASUS VG278 27" monitor, Windows 7 Home Edition
Open Skyrim.ini (My Documents/My Games/Skyrim) and add the following to it:
[Papyrus]
fPostLoadUpdateTimeMS=500.0
bEnableLogging=1
bEnableTrace=1
bLoadDebugInformation=1
Afterward, in that same folder you will see a new folder called Logs. Inside that: Script. Inside Script you will (eventually) find 4 logs. Double click and they should open with notepad or any text editor.
Papyrus.0.log is the most recent.
At the end of it you will see the last process to happen before the crash.
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and you can do this:
Use this with the SKSE install, go to skyrim>data>SKSE and create "SKSE.ini" and type:
[General]
ClearInvalidRegistrations=1
Save and close.
It will now clean invalid scripts from mods you don't use anymore from your save game. It will take a while and only works as you play.
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Beside that:
You cannot remove any mod, not even the patch, without there being some data that's been permanently changed.
Doing this repeatedly WILL damage your save and WILL eventually lead to it becoming corrupt and unusable.
Bethesda's own developers have confirmed the only way to properly remove a mod is to load a save made BEFORE that mod was introduced into the game.
If you started a new game with 10 mods installed foe example, you're going to be stuck with those 10 forever.
See this utility, can clean save files (Prob not completely - but might solve your issue):
Skyrim Save cleaner: http://skyrim.nexusmods.com/mods/31724//?
How to REMOVE ALL embedded scripts from your savegame - Tutorial: http://skyrim.nexusmods.com/mods/31675/?
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As for the Dragonborn i go try it myself and see what happens. (Only curious !!!! - btw i have installed the new unofficial patch today 1.3.3 (it came out yesterday i think), and it fixes a lot of things.
http://www.iguanadons.net/Unofficial%20Skyrim%20Patch%20Version%20History.html
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btw my PC configuration is: Dual Pentium G2020 (2.9 Ghz) - mini ITX Asrock MB - Gainward GTX 660 Gold - 4Gb 1600MHz@1333 - Samsung SSD 840 120 GB. (i play on high settings - A/A disabled, Vsync=enabled)
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I have the exact load order as PieLighter stated. (all official and unofficial patches, all DLC's. and the HD textures mod.)
No freeze so far, no ctd's (fingers crossed)