I rather recently got the game with all DLC's. I played it a little and now I am planning on playing the game on very difficulty, hardcoe and with Ironman (no mods).
I have the following build in mind:
ST 4
PE 5
EN 9
CH 5
IN 6
AG 6
LK 5
Traits
Skilled
Good Natured
Perks
Intense Training (Strength)
Educated
Toughness x2
Hand Loader
Strong Back
Travel Light
Commando
Pack Rat
Stonewall
Animal Friend
Math Wrath
Action Boy x2
Life giver
Sniper
Silent Running
Jury Rigging
Light Step
Adamantium Skeleton
Better Criticals
Grim Reaper's Spirit
Nevers of Steel
Rad Adsorption
Thought you Died (because I will play with good Karma)
Now Animal Friend and the high Intelligence is mainly for roleplay reasons, I am aware that it forces me to have a too high Charisma. For everything else I would like to hear your advice.
I was also thinking about the perks "Hit the Deck", Finesse and Solar Powered.