Thank you. Does adjusting the mouse sensitivity make any difference to the game? I've never played the first two Fallout games so I'm not sure.
In all honesty, I'm not sure as I've never tried that. Maybe it will, but I seriously doubt.
On the subject I've checked out the crossover forums regarding Fallout, I've read that the version pruchased from GOG.com is stable albeit sometimes the mouse will act up when ran in windowed mode. According to the post, running in fullscreen mode is out of the question, although he ran it in Linux using Crossover for that OS (but I don't expect many differences in performance.)
http://www.codeweavers.com/compatibility/browse/name/?app_id=3451;forum=1;msg=45159