Who'd have thought a random vampire attack would be helpful? I'd just finished talking to him about entering the house when a Master Vampire and two Death Hounds showed up and killed him. It flashed up, "Failed: House of Horrors." Tyranus was the only person who died before the undead were dealt with. Now I don't have to start that damn quest just to get him to stop pestering me to help him. I thought he was essential until you were inside but looks like I was wrong. Abandoned house will stay locked and abandoned forever. Best random vampire attack ever.