I am currently playing a vigilant of Stendarr play through using alternate start and requiem overhaul (highly recommend requiem if you haven't tried it) and looking for suggestions on how to handle the daedric artifacts quest lines.

Should I
a. Avoid them completely
b. walk into them blindly and choose the options that defy the dedra (which often times end up in getting the artifact anyway.
c. Do the quests with the intent of hiding away the artifacts so they can not spread their vile corruption.

I'm a bit conflicted here, because as a vigilant your Divine purpose is the complete irradiation of the daedra and less evils vampires, wearwolfs, undead ect. Artifacts like dawn breaker aid in this mission. Any suggestions are appreciated...

They might aid the mission, but you are still giving the prince power by using it's artifact. Collecting them to lock them away wont work either, since the Daedra determine who gets them and for how long (according to lore, more or less.) You're best bet would be A) and slaughter Daedra worshippers when you find them.

Completely avoid them. With the exception of the one at Dawnstar.

As long as you:

In response to your signature, The sword for Nazeem. I would use my hands to throttle Delphine (more satisfying). I kinda like Maven, but I could find a way to seal her in a building, and then burn it to the ground.

The signature is a play on "essential" characters. You wasted it on Nazeem(who isn't essential), so you cannot kill the other two :c