Which of the weapons in Fallout: NV do you feel you can draw the most overall use out of, as in a weapon that you can trust as your main armament for a large portion of the game?

My #1 pick would be the Laser Rifle, I picked it up very early in the game at lvl 6

and it stayed with me throughout, until the end battle at lvl 42 which it dealt with in a matter of seconds. My character was a fast shot with the laser commander, better criticals and finesse perks and the Laser Rifle just ate up opponents. What I like most with it is that I could use it both as a long range sniper rifle, and for close range cleanup, no matter what situation, the Laser Rifle did the best job.

The power fist can also be obtained fairly early and stay useful throughout a long game, but as a melee weapon it is more situational since you have to get to your opponents first. The 12.7mm submachinegun, although introduced a bit later, was another weapon that I drew a lot of utility from with one of my characters.

But can anything rival the Laser Rifle for sheer utility value? Sure it breaks down quickly, but repair is cheap and after a certain point in the game, you can scrounge up weapon repair kits pretty much anytime you need them.

Little Devil, I can snipe with it, and 12.7 is surprisingly easy to find in the game. Put a silencer on it, and it's even a stealth weapon. Only downside is the clip only holds 7 bullets.

My problem is my aim is terrible, so I end up missing half of my shots, so with only 7 bullets I don't have enough to kill things. The LR holds enough ammo and fires quickly enough to make up for my lousy targeting.

Devil requires good strength and a decent to high amount of skill, if your skill or str is lower, it will make your gun sway like a dancing girl. pop a steady and you will shoot like a pro:D

Best utility weapon for me might be the Hunting Shotgun.

With all three mods, the two shotgun perks, and the different ammo types, it is good for everything except long-distance sniping.

And pretty fair at medium-distance sniping anyway.

In terms of the weapon I use most it would be the modded Varmint Rifle/Ratslayer . I actually have to make characters where I'm not allowed to use it to keep the regular fights challenging. For the tough fights though A Light Shining in the Darkness usually ends up being my go to gun and the modded War Club is my flyswatter.