I don't remember seeing weapons with cross stats. ie a bow that has +healing or a two handed axe with +destruction. Anyone have any insight on this? Or is it just runes?

From what I remember, weapons don't provide direct skill boosts, which wouldn't do much under the game's skill system anyway. They can be enchanted (via the runes/enchanting system) to provide a damage boost per hit, and their inherent traits (which can be researched and applied as part of the crafting system) affect other values. In the latter case, every weapon can potentially have every trait, but they're general stats that don't link specifically to any one weapon skill.