Here is a copypasta of my post on the Nexus:
After having an innkeeper or stable keeper refill my waterskins I can no longer talk to them.
I can't enter dialogue in any shape or form. Even after uninstalling the mod I cannot talk to them. I've tried resetting thier AI and disabling them, no fix yet.
So right now, I can't talk to a vast majority of the innkeepers in skyrim, please help!
Now it seems that this issue is spreading randomly. The shopkeeper at Riverwood refuses to talk to me. Any advice would be much appreciated.