- Operation Anchorage, right after Waters of Life.
The Enclave is coming full force, you need allies.
The Citadel just opened its doors, to provide help.
Maybe the outcast would do the same.
Turn out they have gear to share, but it isn't for free.
- Broken Steel
Right After the main quest, to finish the ennemy.
- The Pitt
You dealt with Capital Wasteland issues, activated the purifier and avenged dad.
Now you can care about the issues of other territories.
- Point Lookout
You dealt with The Pitt issues, you can take some vacations. (at least, it appear so initially)
You'll get some personnal insight during a weird ritual.
- Mothership Zeta
You are basically jumping the shark. So better do it in the end, when all other plots have been hexausted.