Once outside the starting area of Goodspring I start experiencing pauses where the game simply stops and my PC becomes completely unresponsive for anything from 3 seconds to 30. This happens at intervals of 5 to 60 seconds, and only in areas outside the starting town. It does not seem to be related to the presence of NPCs or MOBs, use of VATS, etc. Once a pause ends the game runs as silkily as before, so it doesn't feel like stutter (too long and sporadic) or lag (too silky smooth outside the pauses).
The game is utilising about 50% of my CPU (manually capped at 2 cores), requires only 0.6gb of system RAM, and does not access the HDD during these pauses. The game runs smoothly (40+ FPS) on Ultra and High graphics settings, and will keep pausing even when set to Medium with low textures.
Game process is set to 'above normal' priority to fix the missing speech/delayed effects bug. Steam set to run in offline mode. Unnecessary system hogs like anti-virus disabled.
I'm running a quad core Athlon, ATI Radeon 4870 (1gb), and a lowly 2gb of DDR2 RAM on a WinXP SP3 machine, latest drivers, etc.
I'd greatly appreciate any advice on this.