This problem occurred a few days ago after patching USKP. I went up to my spouse and got money from him from the store. However, he no longer wanted to sell me merchandise (nor, could I sell anything to him.) The dialog line is no longer there after I got my store money. Subsequently, shortly after that he left home and never came back.

So, I reverted to a previous save, I loaded the remainder of the Unofficial patches, made sure most of my other mods are updated (ok there are a few more I have to look at, gotta admit), sorted it all with LOOT, and well, I just went on to play, etc. Today I came back home and the same thing is happening. I get our money from the store and he loses the line to buy/sell.

Has anyone else seen this? What could be causing it?

Are you sure it's USKP related, and not one of your mods fault ???

Except you are using one of those mods, with the USKP installed.

http://afkmods.iguanadons.net/index.php?/topic/3636-mods-made-obsolete-by-unofficial-patches/