I use quite a few population mods in my game, including iqNPCs, iNPCs, PCTV, Populated Roads, Immersive Patrols etc., but one problem I've been having is with some of the custom NPCs. For some reason, they've been made to be hostile to any vampires, friendly or not, even Serana. The mod I've narrowed down to as the cause is Erkeil's Populated CTV where it's mainly the Hunter and Labourer NPCs that will turn hostile. The Labourer NPC may actually be from Inconsequential NPCs instead, I don't really remember.

Anyway it's becoming a big annoyance for me, especially with Serana as my follower. The NPC attacks Serana, Serana kills the person, city guards become hostile to her, end up causing a big riot.

I've looked into Erkeil's mod but couldn't find anything wrong about it. But I don't know, I'm no expert at this sort of NPC spawn mods.

There was at least one other fix I've managed to find... and that's removing the vampire faction for the particular vampire NPC, which I did through console commands. I tested it on the iNPC, Edwayne, and that worked out pretty well, with no more hostility toward him.

I guess this same tweak would work for Serana but I'm unsure on the consequences on doing it on such a important NPC. So is there any risks in removing the vampire faction from Serana? Will she still remain a vampire after that?

And of course my utmost concern is whether this might break any DG quests...