I also have some mods but mainly horse ones.
Well, the game does actually have bazillions of bugs. If you haven't installed Unofficial Patches yet, you really should. They exist for a reason.
You may need to revert to an earlier save to fully prevent quest related bugs from occurring.
As KirottuD mentioned above. Actually, those bugs and glitches can happen randomly. They can't affect your first game-through, but can occur on a second one. !!!
If those mods you are using, *are compatible with the USKP, then you should definitely install it. (*you can check that, on the installation description of your downloaded mods)
After you install the USKP, go and load a save before the glitch happened, and then make a new manual save.
load the save, wait for (31 in -game days), and make a new save again. Load that last save, and proceed from this point on...with your game.
Make sure SKyrim is fully patched also. If you have a good Internet connection, this should have been done already.