In ini the most notable is ipreloadsizelimit, which I read by Martigen was (few years ago) recommended to set quiet low, about 3x bigger than default for Fcom and few mods in my case. The most recent posts about Oblivion performance I've seen users using large values, few times bigger than mine that take the whole PC ram.
Also OSR critical section seems to be interesting and sometimes changed.
I'm using some newest mod community tools such as Oblivion reloaded purger, moreHeap.
I'd like to see your view on that matter.