That's what I'm doing right now.

Kaylee was born in Rivet City, grew up in Vault 101. After her dad escaped to finish Project Purity, she escaped after him, went though a whole series of madcap adventures (working for Moira, failing the Big Town mission, rescuing Ian West from the Family, repairing GNR's antenna, etc.) After the final showdown with the Enclave and finally completing Project Purity, Kaylee left the Capitol Wasteland behind and spent the next three years hiking across the former USSA before finally settling down in Primm and working as a courier for the Mojave Express. Until she was ambushed near Goodsprings on that fateful night in 2281...