it seems we have new Vault this is pretty exciting judging from what i saw of the trailer we may also get a playable prologue of some description. I assume that ends with us reaching the vault and the door closing behind us. You will probably play this from one of your ancestors perspectives and it may act as a kind of tutorial.

I noticed also ships like troop or drop ships so we may be getting some kind of transport in this game (possibly like the cart in Skyrim) They focused a bit on a dog in the trailer so this leads me to believe that we will be able to buy at some point or be given a dog in the early game.

I noticed that we here a protagonist talk. People are saying that this will be the voice of our protagonist. I don't buy it I think the voice is just for dramatic effect all in all I am impressed yes the graphics are not AMAZING but remember this is possibly an early build of the game and it is still fallout after all.

I get chills every time i see a mushroom cloud. It makes C&C games very difficult to play. I may also be a horrible person...

Overall, it was more than i was expecting. Lighting seems good, it's a little more scrub-brush than we're used to seeing... It was a much more through teaser than the one for Fallout 3...

It also had a more emotional impact to it with the whole Dog presence... But i love animals so that may just be me. Had me going for a bit, thinking this was going to be set very soon after the war.

http://www.gamesas.com/topic/1519024-fallout-4-speculation-ideas-and-suggestions-261/ is a good thread for this discussion.