Ok, I have 10 STRENGTH and 100 GUNS, I'm using the Ranger Seqouia with the Hand Load rounds. I'm doing the "Come Fly With Me" quest, and in the basemant. The gun seems to hit EVERYTHING but the Super Mutants. Getting really annoying, rounds can e expensive and rare, so any tips? Gets to be the point I'm reloading 3 times before they are put down.

Are you using VATS or free hand shooting with the iron sights?

What difficulty level?

Dificulty Normal

Both vats and free hand with iron sights

I havent seen too many problems with rangr seq, or the hunting revolver for that matter. Though oddly enough, when i use a .44 i swear that thing's barrel is bent to the left about 180 degrees lol, even with max guns etc guy misses like no body's business. I have played this game for years and that is the one gun that has always been my fave to see and get and then miss miss, sold, or on the shelf in my hideout collecting dust. This even includes the Mysterious Magnum, pretty, but for some reason in my games it cannot hit crap lol