Cross-posting this from Reddit, to cast a wider net, as it were. Edits made from original to reflect updated information.

This is possibly the strangest issue that I've come across yet in three years of modding Skyrim, and I have no idea where to even start looking for the cause.

On my current playthrough, I've made absolutely no changes to my mods - updates, removals, or additions - and have had a quite acceptably stable run up to this point (no more than 1 random, un-reproducable CTD per few hours of play). I have no idea if the numbers mean anything, but about an hour after I hit my 98th save at ~60 hours in, I had another random CTD in Riften, at which point I restarted Skyrim and tried to load my latest save (an autosave after exiting Black Briar Manor, I believe) which then caused a CTD on load. After trying each save in reverse order, I found that I can load save 98 - or any save preceding it - perfectly fine and continue playing from there, but any save created after that will cause a CTD on load - no matter what variation I take in my course of action (going to Whiterun instead of Riften, for example). The only exception to this that I've found is after I tried loading save 99 (made ~40 min of gameplay later) and CTD'd, I loaded save 98, walked several steps, and immediately made a save (save 100). That save loads fine, but still has a CTD on loading further saves made from it. Starting a new game works as expected, and does not cause a CTD.

To go through the requisite information: I use Mod Organizer, a slightly modified LOOT load order, have a bashed patch, and used TES5Edit to clean my plugins and merge some patches and armor mods.

My computer specs are as such: AMD FX-8320 8-core CPU with 12gb RAM and a GeForce GTX 760 on Win7.

Modwatch link for my mods: http://www.modwat.ch/u/Erroi

To my memory, I've made no INI tweaks that I didn't revert, and I don't use any ENB past the stock, graphics-less ENBoost.

If someone has any idea what might be happening, it would be much appreciated.