I could use some help, whenever I start trying to play Skyrim on my PC with my wired Xbox 360 controller, the mouse and controller malfunction and stop working. The mouse keeps flashing and the controller does nothing. But I can get the controller working again if I unplug and plug back in again, while I have to restart the computer for the mouse to work again. My keyboard is not affected. This ONLY happens while playing Skyrim, about a minute in. No specific area in the game. I'm wondering if it's the mouse, but then why would the controller stop working? Any ideas would be appreciated.

Have you connected your XBOX360 controller and the mouse to an hub ???

For best results, plug the controller into a USB port on the back of the computer. !!! (and for the mouse as well)