As of today, FO3 crashes to desktop 100% of the time when entering another zone. I've set game to run as administrator, I've set it to run in compatibility mode for XP sp3, I've removed all mods except the unofficial patch, I've done the recommended edit to the .ini file, I'm loading from a saved game instead of an autosave, I've even tried starting a completely new game without anything but DLC and the unofficial patch, but it still crashes to desktop every time I try to leave vault 101. I'm really at a loss here, the only two things I haven't tried are a total reinstall, or resetting my computer to use Windows 8.1, and the latter is just too drastic IMO...