I always tweaked my safe zone UI so they be more at the edge of the screen instead almost at middle of screen.

This only applies to the UI,like HP,Compase,ammo count,Light on Icons etc.

They cannot be configure individually,you need a mod for that.

For some reason Bethy forgot to add an "e" and the end of " fSafeZoneYWid=36.0 "

The code can be found in the Fallout4.ini

The default code is as follow.

The one I use for wide screen is this two.

But Bethy forgot to add an "e", so any numbers you mess with will not take effect intill you add an "e" .

This what I'm using to make the UI close to edge of the screen which give me more view in the center of the screen with out to much UI intrusive.

Here's a pic to show the defualt location and my tweak to better explain what this tweak does.

http://s10.postimg.org/8tyiin3s7/Fallout4_2015_11_25_12_13_15_97.png