So I just completed a safe house mission for Desdemona and I need to turn it in for the reward. The problem is, I'm also at the point during the Molecular Level where I need to decide which faction I'm going to tell about the Signal Interceptor. I'm unable to turn in the safe house mission because two of Desdemona's dialogue options lead to the Molecular Level quest.

So my question is, if I give her the information, does that lock me out of moving on with any of the other factions? It's not the biggest deal, I'll be playing through many times, but this is my first run and I want to take a bit more time to decide.

Please keep spoilers to a minimum, thanks.

Oh-kay, simultaneously specific and circumspect, huh? Short version is that you're only looking for assistance in reading Virgil's notes/plans and then building the silly thing. If, for example, you ask Faction A for assistance and your standing with them is good enough to get it, then Faction B and C don't know or don't care and it doesn't affect your standing with them.

Ah, good. It really just comes down to me wanting that little XP boost for turning in the quest to Desdemona.

Also, I'd like to add that just because you enlist one faction to build the teleportation device, you don't have to stay with them the entire time. For instance, I recruited the Brotherhood to build the device...but in very short order I betrayed them and went Railroad as well. You only need the relay for the initial trip into the Institute. After you complete the introduction to the Institute quest (basically a glorified, semi-guided tour), you'll be given permission to come and go as you please.

That's exactly what I wanted to know. Thanks.