I would be surprised if I can actually enjoy playing a post Oblivion Beth game. I got more joy out of wrecking FO3/4 and Skyrim rather than playing them. Therefore, I can't decide whether to hate FO4 now or later. All the fancy bells/whistles/gimmicks are nulified if the npcs are contemptible jerks and the quest[s]/questline terrible. If this game is made by the same people who made the above three, then I expect that nothing has changed as they will stay in their comfortable rut and regurgitate the same general pattern of game functions and questlines.
For those who played the demo, is the game lighthearted and cheerful like Oblivion or unhappy and miserable like Skyrim?
Are the npcs autonomous as if they were 'alive', as if there were other 'players' in the game [Oblivion] or are they repetitious script puppets with repetitious dialogue, running around in circles [Skyrim]?
Even the villains in Oblivion were likeable, with exception to Jenessa, Mike the Liar and the traveling merchants, I exterminated 2/3 of FO3/4 and all of Skyrim.