I sure hope it's an option, although I have my doubts Bethesda will include it after Skyrim. They had a perfect setup for it in that game, with crafting stations for cooking and everything and... nope, not included in the base game. Had to wait for other players to include these options via mods.
In the Fallout setting, certain other options generally associated with hardcoe mode should just be the default for that mode - stimpaks healing over time and ammo having weight come to mind immediately. I'd almost be willing to argue that they should just be the default, period without a hardcoe mode but I know many players wouldn't like that so including it as an optional mode would work instead.