While I like the idea that there are no "dump stats" any more, the flip side is that if ALL stats are important, it really really hurts to specialize. In my case, I usually ignore STR and END since I rarely melee and as a sneaky sniper who carefully plans fights, I rarely take much damage. But STR affects carrying capacity so having a low STR means more trips to the base to store stuff, or a merchant to sell them, or simply NOT looting as much stuff. And both stats may influence some perks. So I may end up raising them above 1- 2 for that reason.
Intelligence, Luck and Charisma have pretty ill-defined roles / effects at this point. If Intelligence is purely for xp gain, I know a lot of people (like me) are in no rush to level and would lower it. Charisma deals with conversations ~in some way~ and since I play FOR the story and dialog and such, I would want to have as many options as possible. But if the only real difference between a 1 and a 7 CHA is one more dialog every now and again, I have to weigh that against practical concerns. A low Luck would mean not as much rare stuff being looted, less criticals, etc. Things that you might not notice. In Fallout-3 I'm playing a 2 Luck character, and I've had my gun jam like three times so far (level 10ish ) which is irksome but hasn't got me killed yet. So Luck might be a dump stat for me (it sure is in real life, heh heh).
S - 1
P - 6
E- 1
C- 6
I- 6
A- 7
L- 1
Unfortunately, I imagine I'll get frustrated that my raised stats are not showing a LOT of improvement and my lowered stats are hampering me too much, and I may end up with 4's across the board, or three at 2 and three at 4 and two at 5. Only SLIGHTLY above average in a few and only SLIGHTLY below average in a few. For some experimental runs, though, I'd like to try a build with two 10s (assuming that's the max) and one 4 with the rest stuck at 1. Like, one build with the 10/10 pair being STR/END (melee monster), and another one being PER/AGI (Super VATS use), and another one being INT/CHA (Smooth Genius) and MAYBE one with 10 LUCK just to see what that really does for you.
EDIT: Spelling.