I'm wondering if a decent amount of items in this game are in static locations sorta kike how they were in 3 or is it pretty much all random and scaled to level? It doesnt look to be a problem either way based off of what I have been seeing but I'm just curious.

From what I've seen so far, it looks like a good mix. Awesome items can drop as loot but there are some equally awesome items in fixed places. The Cryonator for example. I also came across an amazing melee weapon that I can't get yet. Legendary enemies drop the best loot (obviously) but their appearance rate depends on difficulty level. IMHO, it's the best of both worlds.

Thanks for the reply.

I've only found one unique weapon so far, so I'm not sure if the same can be said for all others but it has an asterisk displayed next to it's name.

Big Jim* is how it shows up. It's a wrench that I've attached a very sharp spike to, and it's incredibly fun running around with it being soaked in blood.

Does loot in containers respawn?