I've been waiting for a week now without being able to play Fallout, but the beta patch didn't fix the issue either.
At some point on the way through the main mission, the game decided to get corrupted and that corruption has infected all my save games. I only noticed at a point much later, when all quick- and auto-saves were already overwritten and I decided to reload a quick-save after a failed pickpocket attempt. Now every time I load any of my save games Fallout 4 instantly crashes to desktop. And since I have no backups whatsoever my progress of almost a month now is completely destroyed.
I've uploaded my save files here (in case anyone wants to take a look): http://arstwo.de/fallout/saves.7z
I've run through every option I could come up with, including complete re-install, beta patches and everything else. The game works fine with any other save, but these instantly crash it. And after a month I don't really want to start from scratch again. If anyone has any ideas of what else I could do to fix that, please feel free to suggest it, I am desperate. =(