All the creatures and npcs belong to one or more factions, which give them disposition boosts to members of the same and allied factions. Becoming a vampire yourself is treated as a disease, giving you bonuses, penalties and special effects, but cannot give you membership of the vampire faction. You are still just the player character, but altered, so they are supposed to attack you.
The factions can get complicated, for example not only does membership of the vampire faction give them +100 disposition to other vampires, but +100 to non-lich undead. This is to stop the ghosts and skeletons you can find in their lairs fighting with them. If the game put you in the faction, normal undead would not attack you either, which would be an unfair advantage to the player.