There is simply more of something for everyone in F4, if it is as advertised.
How many of the people who bought Skyrim will buy F4, simply because it is a Bethesda game?
I know that's why I bought Skyrim.
Let's just say, hypothetically that everyone who bought Skryim buys F4. That's a tie.
Now pour on the FPS gamers who aren't into fantasy games, the minecraft types that want to build settlements, and then those who will be interested in using mods- aside from Halo Forge (which I don't think will be comparable) this is unprecedented.
It isn't just that it is a well known, money making series. It has much more to offer.