Okay, I'll start by saying, yesterday, I reported a bug to Bethesda that happened to me. I thought it was just because of death.
(Which I've discovered, is in fact, not due to death at all.)
Edit: I'm playing the PC version. Windows 7 64-bit.
(This is the less important report I made, so skip to the next section if you're interested in the game-breaking part.)
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I saved before entering a building. Upon entering the building, I ran over a bottlecap mine. It exploded, and I made it away in time to stay alive.
Directly after, I ran into a second bottlecap mine. It blew me up, causing me to die.
First, I paused my game, then I reloaded my autosave from entering the building, and the bottlecap mines were no longer there.
(I'm almost sure this has had to happen to someone else).
So, since I wasn't very far in the building, I loaded the save from outside, and as soon as it started loading, I heard the sound from when you die.
I'll just call it the "death animation sound".
So, once the game was loaded, I entered the building, and the bottlecap mines were there.
I assume the game had thought that the bottlecap mines had already exploded when I reloaded the autosave from entering the building.
(Important, possibly quest-breaking part)
Today, I decided to visit The Memory Den in Goodneighbor.
I looked around a bit, and decided to head upstairs.
I saved my game before I hacked Irma's terminal.
After hacking Irma's terminal, I went downstairs. I spoke to Kent Connolly, which was an objective of the Silver Shroud quest.
After speaking to Kent Connolly, I received the next part of the quest, to retrieve the Silver Shroud costume.
I left The Memory Den.
After leaving The Memory Den, I loaded my save from before I hacked Irma's terminal.
Not only do I find that Irma's terminal is already unlocked, (which, it wasn't when i made the save), but, I could not speak to Kent Connolly at all.
No dialogue options whatsoever. The game thinks that I had already hacked Irma's terminal, and spoken to Kent Connolly.
But, my quest menu tells me that I have NOT spoken to Kent Connolly, and I do not have the next quest objective.
So, by loading a save after completing some things, the game will think that certain things have already happened.
This can be gamebreaking, say, if I decided not to talk to Kent Connolly and went on with the game, I would have never been able to return and speak to him.
This has probably happened to others, as well.
It is only fixable by quitting the game, and then loading the save from before you did anything.
Which is in my case, hacking a terminal and speaking to Kent Connolly for the Silver Shroud quest.
I believe this bug is applicable to the following, so far (as tested/noticed):
Mines, terminals, traps, and important NPCs (those who have any sort of dialogue).
The bug is easily replicated, and I suggest you try it yourself. If it does in fact happen to you as well, I recommend a feedback report.
I just thought I would inform people, so they may know what's going on if this happens to them, or they are unable to finish a quest.
Thank you for reading, and have a great time in the Commonwealth, folks.
- InConSciOUS, trying to help fix some little kinks in this excellent game!