I was so sad when I found that Fallout 4 didn't have hardcoe mode :,(
I hope the next Fallout they make will put in a hardcoe mode like in New Vegas but expanded.
The stimpacks shouldn't heal limbs, if they do I never experience gameplay without a limb, use doctor bags.
Theres too many items in the game to loot, I never run out of stimpaks and fusion cores(at least I run out of ammo in survival mode)
Maybe they could expand the radiation system, like mutations and that sort of things that would be an awesome feature.(Theres so much that can be done on this)
Also I think they gave you the power armor too soon.