I know it is really early to start discussing future DLC, but I think it would be great if in one of the DLC the player sets sail to either the capital wasteland, or somewhere in western Europe. This could work since there is a huge coastline to the east. Re-visiting the capital wasteland would be really cool and nostalgic, and visiting Europe would be equally fun as I don't think Europe has been touched in previous fallout games.
What's your thoughts on possible locations?