You are at the end of the game not sure why you think you are hosed unless you didn't want to side with the Institute but the game is pretty clear before you start the Mass Fusion quest that there is no turning back at that point.
Have you spoken to the guy in the institute you meet in a store room?
Yeah I think you have gone to far if you have been the the mass fusion building but it should have auto failed all the faction quests. Since it didn't I don't know but I seem to remember that guy didn't want to talk to me once it became known I was next up for the directors chair.