When sent here to clear for either Railroad or BoS, you may clear it and the map says cleared but the quest won't detect that you cleared it.
Exiting Sedgwick Hall and re-entering via the rear door will sometimes spawn the remaining enemies you need but this solution isn't 100% effective.
It may be caused by clearing University Point before being sent on a mission as some enemies don't respawn properly and thus not enough kills are being detected.
A possible workaround would be to wait longer and see if everything respawns.
If not, reload a previous save before you did the "clearance" in that area (without getting a quest to do so)
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There is a much proper solution for this, but it affects PC only! (through console commands)