Hi, the new beta patch appears to completely break crossfire support.
In the non-beta version I'm able to get great performance with two Radeon 390s (using AMD's AFR setting).
With the new patch, AFR no longer works. I've tried multiple graphics settings combinations including HBAO+, SSAO, no AO, and different AMD profiles, but all have huge graphics bugs.
Please fix crossfire support before releasing the patch - I bought two 390s specifically to play Fallout 4 maxed out and it looks awesome!