Just curious to see what other people are doing. Wandering the wasteland can certainly fill up your inventory quick. So aside from the usual stop off and drop off all the junk I have been hauling around I find it helpful every so often to just drop pretty much everything right down to my skivvies and then re-equip myself. I am curious, what are your must haves? If your not setting up for a specific mission but just a little exploration around the commonwealth what do you load out? What are your essentials for food, chems, weapons, etc??? As annoying as it is I have come to realize that I cant keep every frag grenade and mine I have ever collected in my inventory and I am finally starting to come around to realizing that some of the specialized food items actually make sense to keep you eating (and sleeping) on a regular basis but again having an insane number of anything but stimpaks is almost counter productive.

A few good guns, 10 rad away, 10 rad x, 230 stims, 10 addictol some clothes and armor and all my msc items

My Doom inspired character carries all the guns similar to that of Doom (Ripper for chainsaw, double barrel shotgun, plasma rifle, minigun for chain gun etc. I'm still looking for something to use as a BFG though) as well as chems that he uses as power ups. Combat armor and the yellow flight helmet to somewhat complete the look though I wish there was a green version of it. Due to all the weight I have to invest in both strong back and lone wanderer perks but they fit the theme anyway so it's all good.

10mm (fully upgraded) w/15 points of burn damage.

Combat shotgun (fully upgraded - non-auto). I had the Terrible Shotgun, but the recoil was just too bad to make it useful.

Sniper laser rifle. Unlimited ammo.

Guass rifle: fully upgraded, unlimited ammo. 400+ damage. Bar none, the best weapon I have.

Early on, I carried food I cooked, but stopped doing that because it just seemed I was taking more damage than food could recover (mid-level), so I changed over to using stimpaks. Now, I have more Mirelurk, Yao Guai, and Deathclaw meat I can eat.

For my junk hunt, I grab mostly low-weight items because I can carry more than heavy items. Battered clipboards, screwdrivers, cans, and anything else with 1wg or less.

I do keep a pack of bubblegum on me because my character loves her bubblegum. *pop*