Well, this is frustrating. After getting max affinity with Cait, I'm going to have to sideline her because she's complaining about me using drugs, and this character is built to use drugs at every opportunity. I can't even use a Graqe Mentats to sell stuff without her [censored]ing. I never noticed on previous playthroughs because I didn't use drugs extensively before.
Oh well, I guess it's time to go get Valentine and advance the main storyline anyway.