Having played Morrowind Overhaul 3.0 already, I wanted to how these other two compare.

I do not know if it's true but I heard somewhere that it is possible to get Morrowind Overhaul to work on OpenMW. While I've never tried the Less Generic NPCs Mod for Morrowind, I plan on using it in my new playthrough I would like to know if it's is compatible with any of these three as well.

Besides being optimized for modern computers and being open sourced is there any other real differences between OpenMW and vanilla Morrowind?

Not yet any difference, really, seeing as though OpenMW hasn't even reached version 1.0.

Hi! We've moved your thread to the morrowind mods board. This should put your question in front of the appropriate audience!