I was poking around Relmyna Verenim's place in Xaselm, and as I play a thief I went snooping in her closets looking for loot.
I unlocked a closet door and there was Nanette Don lying dead on top of some barrels. Now, mind you, this door was locked.
I'm almost suspicious that she got trapped in there at some point, and when Relmyna was doing some experiments she used some AOE spell(s) that killed her.
I also found it interesting after not playing for a while that when the new Gatekeeper is built and tested, someone familiar is the priest of order that comes to attack it.
Course, that someone is also familiar to Nanette, so it was almost like a Shakespearian Tragedy.