I usually like to play a clean character who helps the needy and says no to drugs, but I recently started a merc character and started dabbling in chems. Now let's me tell you, there great. Something needs to die now? Psycho. Wanna enter the Matrix? Jet. Really need to bash someone's face in? Take some buffout. There is literally a chem for everything. So, what chems do YOU do?

Just started doing this with one of my higher level characters. Had no perks I wanted so I invested in the one that makes them last longer, I make a ton of psychojet and trip balls for 30+ seconds of slo mo and I kill everything in the room. It's really fun

My first character was built around chems. The combo chems you can make are fantastic. Bufftats and psychobuff both last quite a while if you are perked up in chemist, and they stack. Psycho Jet blows VATS out of the water. Graqe Mentats are quite useful as well.

I am partial to graqe mentats myself, makes buying and speech checks a breeze, and psychojet is absolutely amazng. Though the obscure chems like daddy-o or daytripper don't seem very helpfi, which is a shame because I really want to use something called daddy-o.

I tend to use psycho for my vet character too. Love the roar the character makes whenever they take it '[censored] KILL!'. Its a small thing but a very nice touch.

The vice of the weak.

Chems are bad, m'kay? So, if you do chems, you're bad, m'kay? Because chems are bad. they can hurt your body, m'kay? Cause chems are bad, m'kay?

I do psychobuff, bufftats, overdrive, jet fuel, ultrajet and wash it down with yao guai steaks and a dirty wastelander. Still waiting on them to fix fury, best drug in the game and its broken.

Im really glad bethesda added some special effects to chems and not just a stat boost. I was always lame playing a druggie in NV & F3 and not actually getting a high/warped experience with the drugs.

Man most of my guys end up abusing psycho jet haha

mmmmmm makes my blood feel all fuzzy and happy :D:D

So, there are Graqe plants in the game? I have yet to see a Graqe plant, I do have some Mentats though.

Day Tripper. One way ticket, yeah! There should be an animation when you take chems to turn into this guy. http://www.youtube.com/watch?v=EeoYX_OUwY8